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1

Crystallization and preliminary X-ray analysis of Escherichia coli methionyl–tRNA formyltransferase

Emmanuelle Schmitt, Yves Mechulam, Marc Ruff, Andre Mitschler, Dino Moras, Sylvain Blanquet

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1996

Language:

english

File:

PDF, 274 KB

english, 1996

2

Translation Initiation

Blanquet, Sylvain, Mechulam, Yves, Schmitt, Emmanuelle

Journal:

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

3

Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn’s Disease, a Randomized Controlled Trial

Naftali, Timna, Mechulam, Refael, Marii, Amir, Gabay, Gila, Stein, Asaf, Bronshtain, Miriam, Laish, Ido, Benjaminov, Fabiana, Konikoff, Fred M.

Journal:

Digestive Diseases and Sciences

Year:

2017

Language:

english

File:

PDF, 417 KB

english, 2017

4

Adaptive landscape flattening allows the design of both enzyme: Substrate binding and catalytic power

Opuu, Vaitea, Nigro, Giuliano, Gaillard, Thomas, Schmitt, Emmanuelle, Mechulam, Yves, Simonson, Thomas, Onufriev, Alexey

Journal:

PLoS Computational Biology

Year:

2020

Language:

english

File:

PDF, 5.17 MB

english, 2020

5

Crystallization and preliminary x-ray analysis of Escherichia coli peptidyl-tRNA hydrolase

Emmanuelle Schmitt, Michel Fromant, Pierre Plateau, Yves Mechulam, Sylvain Blanquet

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1997

Language:

english

File:

PDF, 30 KB

english, 1997

6

Structure−Function Relationships of the Intact aIF2α Subunit from the Archaeon Pyrococcus abyssi †,‡

Yatime, Laure, Schmitt, Emmanuelle, Blanquet, Sylvain, Mechulam, Yves

Journal:

Year:

2005

Language:

english

File:

PDF, 729 KB

english, 2005

7

Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

Tanrikulu, I. C., Schmitt, E., Mechulam, Y., Goddard, W. A., Tirrell, D. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 921 KB

english, 2009

8

Structural basis for partition of the cyclodipeptide synthases into two subfamilies

Bourgeois, Gabrielle, Seguin, Jérôme, Babin, Morgan, Belin, Pascal, Moutiez, Mireille, Mechulam, Yves, Gondry, Muriel, Schmitt, Emmanuelle

Journal:

Journal of Structural Biology

Year:

2018

Language:

english

File:

PDF, 778 KB

english, 2018

9

Recognition of different base tetrads by RHAU: X-ray crystal structure of the G4 recognition motif bound to the 3’-end tetrad of a DNA G-quadruplex

Heddi, Brahim, Vee Cheong, Vee, Schmitt, Emmanuelle, Mechulam, Yves, Tuân Phan, Anh

Journal:

Journal of Structural Biology

Year:

2019

File:

PDF, 503 KB

2019

10

Structural Bases for 16 S rRNA Methylation Catalyzed by ArmA and RmtB Methyltransferases

Emmanuelle Schmitt, Marc Galimand, Michel Panvert, Patrice Courvalin, Yves Mechulam

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 2.78 MB

english, 2009

11

Use of Analogues of Methionine and Methionyl Adenylate to Sample Conformational Changes During Catalysis in Escherichia coli Methionyl-tRNA Synthetase

Thibaut Crepin, Emmanuelle Schmitt, Yves Mechulam, Peter B. Sampson, Mark D. Vaughan, John F. Honek, Sylvain Blanquet

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 3.29 MB

english, 2003

12

[Methods in Enzymology] Translation Initiation: Reconstituted Systems and Biophysical Methods Volume 430 || Protection-Based Assays to Measure Aminoacyl-tRNA Binding to Translation Initiation Factors

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

13

YB-1 promotes microtubule assemblyin vitrothrough interaction with tubulin and microtubules

Konstantin G Chernov, Alain Mechulam, Nadezhda V Popova, David Pastre, Elena S Nadezhdina, Olga V Skabkina, Nina A Shanina, Victor D Vasiliev, Anne Tarrade, Judith Melki, Vandana Joshi, Sonia Baconnai

Journal:

BMC Biochemistry

Year:

2008

Language:

english

File:

PDF, 5.58 MB

english, 2008

14

Eukaryotic and archaeal translation initiation factor 2: A heterotrimeric tRNA carrier

Emmanuelle Schmitt, Marie Naveau, Yves Mechulam

Journal:

Year:

2010

Language:

english

File:

PDF, 796 KB

english, 2010

15

Mica Surface Promotes the Assembly of Cytoskeletal Proteins

Panda, Dulal, Savarin, Philippe, Joshi, Vandana, Bernhard, Johann, Mucher, Elodie, Mechulam, Alain, Hamon, Loic, Curmi, Patrick A., Pastré, David

Journal:

Year:

2009

Language:

english

File:

PDF, 337 KB

english, 2009

16

Identification of an amino acid region supporting specific methionyl-tRNA synthetase: tRNA recognition

Patrice Mellot, Yves Mechulam, Daniel Le Corre, Sylvain Blanquet, Guy Fayat

Journal:

Journal of Molecular Biology

Year:

1989

Language:

english

File:

PDF, 2.44 MB

english, 1989

17

Lysine 335, part of the KMSKS signature sequence, plays a crucial role in the amino acid activation catalysed by the methionyl-tRNA synthetase from Escherichia coli

Yves Mechulam, Frédéric Dardel, Daniel Le Corre, Sylvain Blanquet, Guy Fayat

Journal:

Journal of Molecular Biology

Year:

1991

Language:

english

File:

PDF, 1.41 MB

english, 1991

18

A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis

Barraud, P., Schmitt, E., Mechulam, Y., Dardel, F., Tisne, C.

Journal:

Nucleic Acids Research

Year:

2008

Language:

english

File:

PDF, 6.24 MB

english, 2008

19

Transition state stabilization by the ‘high’ motif of class I aminoacyl-tRNA synthetases: the case of Escherichia coli methionyl-tRNA synthetase

Schmitt, Emmanuelle, Panvert, Michel, Blanquet, Sylvain, Mechulam, Yves

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 2.29 MB

english, 1995

20

tRNA Binding Properties of Eukaryotic Translation Initiation Factor 2 from Encephalitozoon cuniculi

Naveau, Marie, Lazennec-Schurdevin, Christine, Panvert, Michel, Mechulam, Yves, Schmitt, Emmanuelle

Journal:

Year:

2010

Language:

english

File:

PDF, 1.99 MB

english, 2010

21

Genetic engineering of methionyl-tRNA synthetase: in vitro regeneration of an active synthetase by proteolytic cleavage of a methionyl-tRNA synthetase-β-galactosidase chimeric protein

Hirel, P.-Hervé, Lévêque, Françoise, Mellot, Patrice, Dardel, Frédéric, Panvert, Michel, Mechulam, Yves, Fayat, Guy

Journal:

Year:

1988

Language:

english

File:

PDF, 709 KB

english, 1988

22

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases

Moutiez, Mireille, Schmitt, Emmanuelle, Seguin, Jérôme, Thai, Robert, Favry, Emmanuel, Belin, Pascal, Mechulam, Yves, Gondry, Muriel

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 781 KB

english, 2014

23

The Escherichia coli fmt gene, encoding methionyl-tRNA(fMet) formyltransferase, escapes metabolic control.

Meinnel, T, Guillon, J M, Mechulam, Y, Blanquet, S

Journal:

Journal of Bacteriology

Year:

1993

Language:

english

File:

PDF, 1.47 MB

english, 1993

24

Two Acidic Residues of Escherichia coli Methionyl-tRNA Synthetase Act as Negative Discriminants Towards the Binding of Non-cognate tRNA Anticodons

Emmanuelle Schmitt, Thierry Meinnel, Michel Panvert, Yves Mechulam, Sylvain Blanquet

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 852 KB

1993

25

Methionyl-tRNA synthetase from E coli - A review

Meinnel, T., Mechulam, Y., Dardel, F., Schmitter, J.M., Hountondji, C., Brunie, S., Dessen, P., Fayat, G., Blanquet, S.

Journal:

Year:

1990

Language:

english

File:

PDF, 786 KB

english, 1990

26

Functional Molecular Mapping of Archaeal Translation Initiation Factor 2

Yatime, L., Schmitt, E., Blanquet, S., Mechulam, Y.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 890 KB

english, 2004

27

Critical Role of the Acceptor Stem of tRNAsMet in their Aminoacylation by Escherichia coli Methionyl-tRNA Synthetase

Thierry Meinnel, Yves Mechulam, Christine Lazennec, Sylvain Blanquet, Guy Fayat

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 659 KB

1993

28

Nucleotides of tRNA governing the specificity of Escherichia coli methionyl-tRNAfMet formyltransferase

Jean-Michel Guillon, Thierry Meinnel, Yves Mechulam, Christine Lazennec, Sylvain Blanquet, Guy Fayat

Journal:

Journal of Molecular Biology

Year:

1992

Language:

english

File:

PDF, 1.19 MB

english, 1992

29

Structure and Function of the C-Terminal Domain of Methionyl-tRNA Synthetase †

Crepin, Thibaut, Schmitt, Emmanuelle, Blanquet, Sylvain, Mechulam, Yves

Journal:

Year:

2002

Language:

english

File:

PDF, 239 KB

english, 2002

30

Polyamine Sharing between Tubulin Dimers Favours Microtubule Nucleation and Elongation via Facilitated Diffusion

Mechulam, Alain, Chernov, Konstantin G., Mucher, Elodie, Hamon, Loic, Curmi, Patrick A., Pastré, David, Bonfils, Claude

Journal:

PLoS Computational Biology

Year:

2009

Language:

english

File:

PDF, 964 KB

english, 2009

31

The structure of an E. coli tRNA fMet A 1 –U 72 variant shows an unusual conformation of the A 1 –U 72 base pair

Monestier, Auriane, Aleksandrov, Alexey, Coureux, Pierre-Damien, Panvert, Michel, Mechulam, Yves, Schmitt, Emmanuelle

Journal:

Year:

2017

Language:

english

File:

PDF, 4.87 MB

english, 2017

32

Switching from an Induced-Fit to a Lock-and-Key Mechanism in an Aminoacyl-tRNA Synthetase with Modified Specificity

Emmanuelle Schmitt, I. Caglar Tanrikulu, Tae Hyeon Yoo, Michel Panvert, David A. Tirrell, Yves Mechulam

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

33

Crucial role of an idiosyncratic insertion in the Rossman fold of class 1 aminoacyl-tRNA synthetases: the case of methionyl-tRNA synthetase

Fourmy, Dominique, Mechulam, Yves, Blanquet, Sylvain

Journal:

Year:

1995

Language:

english

File:

PDF, 2.03 MB

english, 1995

34

Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2

Dubiez, E., Aleksandrov, A., Lazennec-Schurdevin, C., Mechulam, Y., Schmitt, E.

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 2.11 MB

english, 2015

35

Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states

Yatime, L., Mechulam, Y., Blanquet, S., Schmitt, E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 1009 KB

english, 2007

36

Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM

Galimand, M., Schmitt, E., Panvert, M., Desmolaize, B., Douthwaite, S., Mechulam, Y., Courvalin, P.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.66 MB

english, 2011

37

Structure of CrystallineD-Tyr-tRNATyr Deacylase: A REPRESENTATIVE OF A NEW CLASS OF tRNA-DEPENDENT HYDROLASES

Ferri-Fioni, M.-L., Schmitt, E., Soutourina, J., Plateau, P., Mechulam, Y., Blanquet, S.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 1022 KB

english, 2001

38

Recent Advances in Archaeal Translation Initiation

Schmitt, Emmanuelle, Coureux, Pierre-Damien, Kazan, Ramy, Bourgeois, Gabrielle, Lazennec-Schurdevin, Christine, Mechulam, Yves

Journal:

Frontiers in Microbiology

Year:

2020

File:

PDF, 6.79 MB

2020

39

Binding of the anticodon domain of tRNAfMet to Escherichia coli methionyl-tRNA synthetase

Thierry Meinnel, Yves Mechulam, Sylvain Blanquet, Guy Fayat

Journal:

Journal of Molecular Biology

Year:

1991

Language:

english

File:

PDF, 397 KB

english, 1991

40

Initiator tRNA Binding by e/aIF5B, the Eukaryotic/Archaeal Homologue of Bacterial Initiation Factor IF2 †

Guillon, Laurent, Schmitt, Emmanuelle, Blanquet, Sylvain, Mechulam, Yves

Journal:

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

41

Three-Dimensional Structure of Methionyl-tRNA Synthetase from Pyrococcus abyssi †,‡

Crepin, Thibaut, Schmitt, Emmanuelle, Blanquet, Sylvain, Mechulam, Yves

Journal:

Year:

2004

Language:

english

File:

PDF, 382 KB

english, 2004

42

Methionyl-tRNA synthetase from Bacillus stearothermophilus : structural and functional identities with the Escherichia coli enzyme

Mechulam, Yves, Schmitt, Emmanuelle, Panvert, Michel, Schmitter, Jean-Marie, Lapadat-Tapolsky, Mary, Meinnel, Thierry, Dessen, Philippe, Blanquet, Sylvain, Fayat, Guy

Journal:

Nucleic Acids Research

Year:

1991

Language:

english

File:

PDF, 4.65 MB

english, 1991

43

Selection of suppressor methionyl-tRNA synthetases: mapping the tRNA anticodon binding site.

Meinnel, T., Mechulam, Y., Le Corre, D., Panvert, M., Blanquet, S., Fayat, G.

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.28 MB

english, 1991

44

Atomic Force Microscopy Imaging of DNA under Macromolecular Crowding Conditions

Pastré, David, Hamon, Loïc, Mechulam, Alain, Sorel, Isabelle, Baconnais, Sonia, Curmi, Patrick A., Le Cam, Eric, Piétrement, Olivier

Journal:

Biomacromolecules

Year:

2007

Language:

english

File:

PDF, 1.82 MB

english, 2007

45

Structure of the ternary initiation complex aIF2–GDPNP–methionylated initiator tRNA

Schmitt, Emmanuelle, Panvert, Michel, Lazennec-Schurdevin, Christine, Coureux, Pierre-Damien, Perez, Javier, Thompson, Andrew, Mechulam, Yves

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

46

Methionine as translation start signal: A review of the enzymes of the pathway in Escherichia coli

T. Meinnel, Y. Mechulam, S. Blanquet

Journal:

Year:

1993

Language:

english

File:

PDF, 1.84 MB

english, 1993

47

Mitochondrial Methionyl-tRNA fMet Formyltransferase from Saccharomyces cerevisiae : Gene Disruption and tRNA Substrate Specificity

Vial, Lionel, Gomez, Pilar, Panvert, Michel, Schmitt, Emmanuelle, Blanquet, Sylvain, Mechulam, Yves

Journal:

Year:

2003

Language:

english

File:

PDF, 271 KB

english, 2003

48

Role of aIF1 in Pyrococcus abyssi translation initiation

Monestier, Auriane, Lazennec-Schurdevin, Christine, Coureux, Pierre-Damien, Mechulam, Yves, Schmitt, Emmanuelle

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 4.30 MB

english, 2018

49

Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates

Bourgeois, Gabrielle, Seguin, JÃ©rÃ´me, Babin, Morgan, Gondry, Muriel, Mechulam, Yves, Schmitt, Emmanuelle

Journal:

Year:

2020

File:

PDF, 7.92 MB

2020

50

Rapid purification of DNA fragments by high-performance size-exclusion chromatography

Jean-marie Schmitter, Yves Mechulam, Guy Fayat, Michel Anselme

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1986

Language:

english

File:

PDF, 170 KB

english, 1986

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